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In this TEDx talk, Prof Tara Spires-Jones will describe how neuroscience research is helping defeat dementia. Dementia is one of the biggest medical and societal problems of our time directly affecting over 50 million people worldwide at a cost of over $1 trillion per year in health and social care. Neuroscience research is revealing the brain changes that cause dementia symptoms. Prof Spires-Jones will share some of the landmark discoveries in the field and highlight her discoveries using novel microscope techniques to peer inside the tiny synaptic connections in human brain samples from people who died from Alzheimer’s disease, the most common cause of dementia. Research has recently led to the first approved treatments that slow progression of Alzheimer’s disease. These new treatments have substantial risks and costs, but Prof Spires-Jones will describe better treatments on the horizon and things we can all do now to reduce our own risk and contribute to the fight to end dementia. In this TEDx talk, Prof Tara Spires-Jones will describe how neuroscience research is helping defeat dementia. Dementia is one of the biggest medical and societal problems of our time directly affecting over 50 million people worldwide at a cost of over $1 trillion per year in health and social care. Neuroscience research is revealing the brain changes that cause dementia symptoms. Prof Spires-Jones will share some of the landmark discoveries in the field and highlight her discoveries using novel microscope techniques to peer inside the tiny synaptic connections in human brain samples from people who died from Alzheimer’s disease, the most common cause of dementia. Research has recently led to the first approved treatments that slow progression of Alzheimer’s disease. These new treatments have substantial risks and costs, but Prof Spires-Jones will describe better treatments on the horizon and things we can all do now to reduce our own risk and contribute to the fight to end dementia. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx