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💉“What if one dose of methadone could transform pain management for outpatient surgery?” Today the APSF is diving into a groundbreaking study published in Anesthesiology & summarized by Brian Thomas, JD. 💡 Researchers investigated the use of single-dose intraoperative methadone in next-day discharge outpatient surgeries. Why? To reduce postoperative pain, minimize opioid use, and improve patient satisfaction—all while addressing the opioid crisis. 📊 This randomized, double-blind, dose-finding study compared methadone to shorter-duration opioids like fentanyl and hydromorphone. Patients were randomized to receive methadone or standard practice and monitored closely for pain, sedation, and side effects. 🧪 Results? Methadone reduced in-hospital opioid use significantly and showed a trend toward less home pain and opioid use over 30 days. 🏆 The optimal dose of methadone was 0.25 mg/kg of ideal body weight. 💊 Methadone may offer safer, more effective perioperative pain management for certain outpatient surgeries. You can learn more here! https://www.apsf.org/in-the-literatur... #PatientSafety #Anesthesia #Opioids #Surgery #Methadone