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Premium Member Resources: https://www.ninjanerd.org/lecture/hyp... Ninja Nerds! In this lecture, Professor Zach Murphy will present on Hypothyroidism. We will discuss the pathophysiology, including the decreased production of thyroid hormones and its effects on the body's metabolic rate. The lecture will include a discussion on the clinical manifestations, such as fatigue, weight gain, cold intolerance, and constipation. The digital presentation will begin with the diagnostic approach, highlighting the importance of TSH and free T4 measurements. Finally, we will review management strategies for Hypothyroidism, emphasizing the use of levothyroxine to normalize thyroid hormone levels and improve symptoms. Enjoy the lecture and support us below! Table of Contents: 0:00 Lab 0:07 Hypothyroidism Introduction 0:56 Primary Hypothyroidism 6:19 Autoimmune-Related Thyroid Destruction 14:39 Infectious-Related Thyroid Destruction 16:57 Iatrogenic-Related Thyroid Destruction 17:37 Wolff-Chaikoff Effect 20:18 Secondary Hypothyroidism 26:53 Classic Findings- Goiter 29:53 Classic Findings- Metabolic Dysfunction 33:34 Classic Findings- Neurological Dysfunction 35:03 Classic Findings- Cardiovascular Dysfunction 38:26 Classic Findings- Reproductive Dysfunction 40:17 Classic Findings- Gastrointestinal Dysfunction 41:31 Classic Findings- Integumentary Dysfunction 45:00 Myxedema Coma 51:33 Diagnostic Approach to Hypothyroidism 55:45 Treatment of Hypothyroidism 57:48 Comment, Like, SUBSCRIBE! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #endocrine #hypothyroidism