Ghrelin the Hunger Hormone | Part 5 Neurobiology of Food Intake | Macronutrients Lecture 41 скачать в хорошем качестве

Ghrelin the Hunger Hormone | Part 5 Neurobiology of Food Intake | Macronutrients Lecture 41

Ghrelin is a hunger-inducing hormone secreted by the stomach when fasting. Subscribe to Nourishable at    / nourishable   This video is part 5 of the Neurobiology of Food Intake module within a lecture series on the nutrition science of macronutrients. Neurobiology of Food Intake Lecture playlist:    • Neurobiology of Food Intake   Macronutrients Lecture playlist:    • Macronutrients Lectures   Follow Nourishable on twitter, facebook and instagram to stay up to date on all things nutrition.   / nourishable   fb.me/nourishable.tv   / nourishable   Lecture Development, Hosting & Post-Production by Lara Hyde, PhD http://www.nourishable.tv Video Production by Robbie Hyde    / chedderchowder   Opening Motion Graphics by Jay Purugganan https://www.c9studio.com/WP/ The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this video is for general information purposes only. References Klockars, A. et al. Hypothalamic Integration of the Endocrine Signaling Related to Food Intake. Curr. Topics Behav. Neurosci. (2019) 43:239-270 Images Figures created with BioRender Ghrelin is a hormone secreted by gastric cells in the stomach during the fasted state. Ghrelin levels are low after food intake. Ghrelin stimulates gastric acid secretion in the stomach to prepare for digestion, and stimulates gastric motility. Ghrelin suppresses afferent signals in the vagus nerve, which eliminates vagal stimulation of the nucleus tractus solitarius in the hindbrain and inhibits satiety. In the arcuate nucleus of the hypothalamus, ghrelin stimulates the agouti-related peptide (AgRP) neurons to release the neurotransmitter NPY to inhibit activation of the paraventricular nucleus to increase food intake. This makes ghrelin an orexigenic hormone.