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Tracheoesophageal Fistula (TEF) Introduction Tracheoesophageal fistula (TEF) is a congenital anomaly where there is an abnormal connection between the trachea and the esophagus. It is a relatively rare condition, occurring in about 1 in 2,500-4,500 live births. TEF often occurs alongside esophageal atresia, where the esophagus doesn't fully develop. Embryology During fetal development, the esophagus and trachea develop from a single tube called the foregut. Normally, a septum forms to separate the two structures. In TEF, this separation fails to occur completely, resulting in an abnormal connection. Types of TEF There are several types of TEF, but the most common are: Esophageal atresia with distal TEF: This is the most common type, where the upper esophagus ends in a blind pouch, and the lower esophagus connects to the trachea. H-type TEF: In this type, there is a fistula between the trachea and the esophagus, but the esophagus is intact. Esophageal atresia without fistula: This is a less common type where the esophagus is completely separated into two blind pouches. Clinical Presentation Respiratory distress: Due to aspiration of saliva or formula into the lungs. Excessive drooling: Saliva cannot be swallowed due to the esophageal obstruction. Coughing and choking: During feeding, as milk enters the trachea. Abdominal distention: In H-type TEF, air can enter the stomach through the fistula, causing distention. Diagnosis Prenatal: Polyhydramnios (excess amniotic fluid) on ultrasound may suggest TEF. Postnatal: X-ray with a nasogastric tube: The tube will coil in the upper esophageal pouch in cases of esophageal atresia. Contrast esophagography: Can confirm the type of TEF and the presence of esophageal atresia. Management Initial management: Maintaining airway patency Preventing aspiration Providing adequate nutrition through nasogastric or parenteral routes Surgical repair: The definitive treatment is surgical repair to close the fistula and reconnect the esophagus. The type of surgery depends on the type of TEF and the presence of other associated anomalies. Complications Aspiration pneumonia: Due to aspiration of saliva or formula. Tracheomalacia: Weakening of the tracheal wall. Esophageal strictures: Narrowing of the esophagus after surgery. Growth and developmental delays: Due to prolonged feeding difficulties. Prognosis With early diagnosis and prompt surgical intervention, the prognosis for TEF is generally good. However, long-term complications may occur, such as esophageal strictures or tracheomalacia. Additional Information TEF is often associated with other congenital anomalies, such as cardiac defects or vertebral anomalies. Genetic factors may play a role in the development of TEF. Early diagnosis and management are crucial to improve outcomes. Conclusion Tracheoesophageal fistula is a complex congenital anomaly that requires prompt diagnosis and surgical intervention. With advances in medical care, the prognosis for TEF has significantly improved.