H2E3 Template-based brain spatial normalization and VOI atlases скачать в хорошем качестве

H2E3 Template-based brain spatial normalization and VOI atlases

In human neurology research the use of standardized brain atlases is common. Application of these VOI atlases relies on matching of images from an individual to a template image that has the same “image space” as the VOI atlas. Ideally, individual and template images should be from the same modality, for same tracer/sequence. Many templates and atlases are already available and shared online. T1- and T2-weighted MRI templates are common, as are PET/SPECT templates for blood flow tracers and FDG. Note that many brain templates, whether PET or MR, are averages of spatially normalized images from several subjects. This can help to remove minor regional variations and left/right asymmetry, but obviously requires researchers to have images from several normal subjects (ideally outside of the study population), and a template/VOI atlas that these subjects can be registered to. Fuse It provides several brain normalization approaches and atlases with templates.