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Jr-Wei Wu, MD, Taipei Veterans General Hospital, Taipei, Taiwan, discusses his research on pre-cluster symptoms in patients with cluster headaches. Approximately two-thirds of patients in this cohort experienced pre-cluster symptoms before the development of cluster headaches, and there was a link between these symptoms and treatment response. This research has significant implications for diagnosis, patient preparation, and treatment strategies. This interview took place at the 77th American Academy of Neurology (AAN) Annual Meeting in San Diego, CA. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.