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Gout - Pharmacology

Struggling to remember the difference between acute gout treatment and chronic maintenance? Confused by how purine metabolism leads to painful uric acid crystals? In this video, we break down the pharmacology of Gout, making it simple, visual, and easy to remember for your exams (USMLE, NCLEX, COMLEX) and clinical practice. ​[What You Will Learn] By the end of this video, you will understand: ​The Pathophysiology of Gout: How purine metabolism works, the role of Xanthine Oxidase, and why uric acid builds up (Hyperuricemia). ​Acute Gout Management: The mechanism of action (MOA) for NSAIDs (Indomethacin), Corticosteroids, and Colchicine. ​Chronic Gout Management (Prophylaxis): How Xanthine Oxidase Inhibitors (Allopurinol, Febuxostat) and Uricosurics (Probenecid) work to lower uric acid levels. ​Pegloticase: A breakdown of recombinant uricase for refractory cases. ​Side Effects & Interactions: Key high-yield facts (like the deadly interaction between Allopurinol and Azathioprine/6-MP). ​⚠️ Medical Disclaimer: ​This video is for educational purposes only and does not constitute medical advice. Always consult with your doctor or a qualified healthcare provider before starting or stopping any medication. If you are experiencing a medical emergency, call your local emergency services immediately. drive notes link:https://drive.google.com/file/d/1hXVp... Time Stamps: 01:13 Classification of drugs 02:11 Treatment of acute attack of gout 04:12 Treatment of chronic gout 08:08 Drug interactions