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Protein Structure and Folding

After a polypeptide is produced in protein synthesis, it's not necessarily a functional protein yet! Explore protein folding that occurs within levels of protein structure with the Amoeba Sisters! Primary, secondary, tertiary, and quaternary protein structure levels are briefly discussed. Video also mentions chaperonins (chaperone proteins) and how proteins can be denatured. Table of Contents: 00:00 Intro 0:41 Reminder of Protein Roles 1:06 Modifications of Proteins 1:25 Importance of Shape for Proteins 1:56 Levels of Protein Structure 2:06 Primary Structure 3:10 Secondary Structure 3:45 Tertiary Structure 4:58 Quaternary Structure [not in all proteins] 6:01 Proteins often have help in folding [introduces chaperonins] 6:40 Denaturing Proteins Further Reading Suggestions Related to Protein Misfoldings: https://www.nature.com/scitable/topic... https://www.scientificamerican.com/ar... Learn About "The Protein Folding Problem": https://www.ncbi.nlm.nih.gov/pmc/arti... Factual References: OpenStax, Biology. OpenStax CNX. Jun 1, 2018 http://cnx.org/contents/185cbf87-c72e.... Reece, J. B., & Campbell, N. A. (2011). Campbell biology. Boston: Benjamin Cummings / Pearson. The Amoeba Sisters videos demystify science with humor and relevance. The videos center on Pinky's certification and experience in teaching biology at the high school level. For more information about The Amoeba Sisters, visit: http://www.amoebasisters.com/about-us... We cover the basics in biology concepts at the secondary level. If you are looking to discover more about biology and go into depth beyond these basics, our recommended reference is the FREE, peer reviewed, open source OpenStax biology textbook: https://openstax.org/details/books/bi... ⭐We have a menu of our resources that complement our videos! Visit https://docs.google.com/spreadsheets/... Support Us? https://www.amoebasisters.com/support-us Our Resources: Biology Playlist:    • Amoeba Sisters Biology Learning Playlist   GIFs: https://www.amoebasisters.com/gifs.html Handouts: https://www.amoebasisters.com/handout... Comics: https://www.amoebasisters.com/paramec... Unlectured Series: https://www.amoebasisters.com/unlectured Connect with us! Website: http://www.AmoebaSisters.com Twitter:   / amoebasisters   Facebook:   / amoebasisters   Tumblr:   / www   Pinterest:   / amoebasister­s   Instagram:   / amoebasistersofficial   Visit our Redbubble store at https://www.amoebasisters.com/store TIPS FOR VIEWING EDU YOUTUBE VIDEOS: Want to learn tips for viewing edu YouTube videos including changing the speed, language, viewing the transcript, etc? https://www.amoebasisters.com/pinkys-... MUSIC: Our intro music designed and performed by Jeremiah Cheshire. End music in this video is listed free to use/no attribution required from the YouTube audio library https://www.youtube.com/audiolibrary/... COMMUNITY: We take pride in our AWESOME community, and we welcome feedback and discussion. However, please remember that this is an education channel. See YouTube's community guidelines and how YouTube handles comments that are reported by the community. We also reserve the right to remove comments. TRANSLATIONS: Hindi Subtitles Credit: Alisha Aggarwal While we don't allow dubbing of our videos, we do gladly accept subtitle translations from our community. Some translated subtitles on our videos were translated by the community using YouTube's community-contributed subtitle feature. After the feature was discontinued by YouTube, we have another option for submitting translated subtitles here: https://www.amoebasisters.com/pinkys-... We want to thank our amazing community for the generosity of their time in continuing to create translated subtitles. If you have a concern about community contributed contributions, please contact us.