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Pancreatic cancer refers to tumors that arise from the pancreas. I will focus on adenocarcinoma of the pancreas. There are other tumours which can be dealt with in other manners but I will stick to pancreatic adenocarcinoma which is commonly referred to as pancreatic cancer. The main stay of treatment for this is surgery. After surgery, we may give chemotherapy. Occasionally if the tumours are very close to certain critical structure like the superior mesenteric artery or the superior mesenteric vein, then we may consider neoadjuvant or treatment with chemotherapy and radiation before surgery to shrink the tumor, removal of the tail of the pancreas is technically less challenging and patients adapt well because there is only a removal and no reconstruction. The head of the pancreas can be safely removed and requires significant amount of reconstruction and generally requires reestablishment of your alimentary tract, your pancreatic duct, and your biliary system. This operation is commonly referred to as whipple operation. This is a complex operation and when done in higher centres can achieve a good outcome. It is important for the Pancreatic cancer to seek care with a team of specialists who are well trained and experienced in this disease process results are very dependent on not only understanding the management of the disease process but also understanding the management of the complications that can come across complex surgery. Pancreatic cancer tends to be aggressive and chemotherapy does help but not to the same extent, as for example colon cancer. With all this in mind, it is important to understand what type of disease process you have, if you have adenocarcinoma, understand if surgery is going to benefit you and then only proceed with surgery. Nutrition overall health of the patient, the reserve in his body, how extensive the disease is. These are determining factors when we make a treatment plan for you for pancreatic cancer.