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This is an introductory video about RANKL/TRANCE, intended for scientists who need to design controls and perform immunoassays detecting TNFSF11/RANKL/TRANCE/OPGL/ODF. It contains information about western blot band size, protein expression, and interesting facts. Uniprot: https://www.uniprot.org/uniprot/O14788 Human Protein Atlas: https://www.proteinatlas.org/ENSG0000... Western blot images on PMC: https://www.ncbi.nlm.nih.gov/pmc/?ter... Anti-RANKL/TNFSF11 Antibody Picoband™ (PB10015): https://www.bosterbio.com/anti-rankl-... TNFSF11/RANKL/TRANCE ELISA Kits Human TNFSF11/RANKL ELISA Kit PicoKine® (EK0842): https://www.bosterbio.com/human-tnfsf... Mouse TNFSF11/RANKL ELISA Kit PicoKine® (EK0843): https://www.bosterbio.com/mouse-tnfsf... Rat TNFSF11/RANKL ELISA Kit PicoKine® (EK1559): https://www.bosterbio.com/rat-tnfsf11... Human TRANCE/RANKL/TNFSF11 PicoKine® Quick ELISA Kit (FEK0842): https://www.bosterbio.com/human-tnfsf... Learn more about TNFSF11/RANKL/TRANCE (infographic and discussion): https://www.bosterbio.com/bosterbio-g... Boster Biological Technology Website: www.bosterbio.com Email: support@bosterbio.com ________________________________________________ REFERENCES Hoffmann, D. B., Gruber, J., Böker, K. O., Deppe, D., Sehmisch, S., Schilling, A. F., Lemus-Diaz, N., Komrakova, M., & Schneider, S. (2018). Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis. Molecular therapy. Nucleic acids, 12, 443–452. https://doi.org/10.1016/j.omtn.2018.0... Singh, K., Piprode, V., Mhaske, S. T., Barhanpurkar-Naik, A., & Wani, M. R. (2018). IL-3 Differentially Regulates Membrane and Soluble RANKL in Osteoblasts through Metalloproteases and the JAK2/STAT5 Pathway and Improves the RANKL/OPG Ratio in Adult Mice. Journal of immunology (Baltimore, Md. : 1950), 200(2), 595–606. https://doi.org/10.4049/jimmunol.1601528 Wang, Y., Li, X., Deng, F., & Yin, R. (2021). Hydroxy-Safflower Yellow A Alleviates Osteoporosis in Ovariectomized Rat Model by Inhibiting Carbonic Anhydrase 2 Activity. Frontiers in pharmacology, 12, 734539. https://doi.org/10.3389/fphar.2021.73...