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Nowadays it seems like you can find CBD in just about anything, with claims that it can cure all sorts of ailments and boost performance, but is this really true? written & narrated by Mark, edited by April Funded by: UPMC Hillman Academy & NCI R25 YES sources: +FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy. FDA https://www.fda.gov/news-events/press... +Peter Grinspoon (2021). Cannabidiol (CBD)-what we know and what we don’t. Harvard Health https://www.health.harvard.edu/blog/c... +Black, N. et al. (2019). Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis. Lancet Psychiatry https://doi.org/10.1016/S2215-0366(19... +Mead, A. (2019). Legal and Regulatory Issues Governing Cannabis and Cannabis-Derived Products in the United States. Frontiers in Plant Science https://doi.org/10.3389/fpls.2019.00697 +Russo, E. B. (2008). Cannabinoids in the management of difficult to treat pain. Therapeutics and Clinical Risk Management https://doi.org/10.2147%2Ftcrm.s1928 +Walsh, K. B., McKinney, A. E. & Holmes, A. E. (2021). Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses. Frontiers in Pharmacology https://doi.org/10.3389/fphar.2021.77... +Millar, S. A., Stone, N. L., Yates, A. S. & O’Sullivan, S. E. (2018). A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans. Frontiers in Pharmacology https://doi.org/10.3389/fphar.2018.01365 +Hoch, E. et al. (2019). How effective and safe is medical cannabis as a treatment of mental disorders? A systematic review. European Archives of Psychiatry Clinical Neuroscience https://doi.org/10.1007/s00406-019-00... +Perucca, E. & Bialer, M. (2020). Critical Aspects Affecting Cannabidiol Oral Bioavailability and Metabolic Elimination, and Related Clinical Implications. CNS Drugs https://doi.org/10.1007/s40263-020-00... +VanDolah, H. J., Bauer, B. A. & Mauck, K. F. (2019). Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clinic Proceedings https://doi.org/10.1016/j.mayocp.2019... +Kicman, A. & Toczek, M. (2020). The Effects of Cannabidiol, a Non-Intoxicating Compound of Cannabis, on the Cardiovascular System in Health and Disease. International Journal of Molecular Sciences https://doi.org/10.3390/ijms21186740 #cannabidiol #biology #science Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation, National Institutes of Health or UPMC.