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Structured MRI Reporting for Soft-Tissue Tumors: A Practical Framework for Radiologists Magnetic resonance imaging (MRI) plays a central role in the evaluation, staging, and management of soft-tissue tumors, particularly in the extremities. Beyond simply detecting a mass, MRI provides critical information that guides differential diagnosis, biopsy planning, surgical strategy, and treatment monitoring. The educational review “MRI of Soft-Tissue Tumors: What to Include in the Report” emphasizes the importance of a structured and comprehensive reporting approach to ensure that imaging findings translate effectively into clinical decision-making. Soft-tissue sarcomas represent a heterogeneous group of malignant tumors arising from mesenchymal tissues such as muscle, fat, fibrous tissue, vessels, and peripheral nerves. Although they account for only approximately 0.7–1.5% of adult cancers, they can result in substantial morbidity and mortality. Surgical resection with negative margins remains the cornerstone of treatment, making precise imaging characterization essential for determining the feasibility of limb-sparing surgery and for identifying involvement of adjacent structures. The article proposes a structured framework outlining key descriptors that radiologists should consistently include in MRI reports. These include the anatomic compartment, site of tumor origin, maximum lesion size, borders and morphology, location relative to identifiable landmarks, and the relationship to surrounding structures such as fascia, bone, and neurovascular bundles. Additional imaging features—such as signal characteristics, enhancement patterns, peritumoral edema or enhancement (“tail sign”), vascular supply, and regional lymph nodes—provide further insights into tumor biology and surgical planning. MRI findings not only aid in narrowing the differential diagnosis but also play a critical role in biopsy guidance and histologic correlation. For example, MRI can identify viable enhancing tumor components while avoiding necrotic areas during biopsy. Diffusion-weighted imaging may also contribute by highlighting areas of high cellularity and assisting in treatment response assessment. However, signal characteristics alone are insufficient to reliably distinguish benign from malignant lesions or to determine tumor grade, underscoring the importance of integrating imaging findings with clinical and pathologic data. Equally important is the evaluation of tumor relationships to adjacent structures. MRI assessment of preserved fat planes, degree of neurovascular encasement, and possible bone invasion directly influences surgical strategy, including the feasibility of limb-sparing procedures versus more radical approaches. Additionally, recognition of peritumoral edema and fascial extension is critical for defining surgical margins and planning radiation therapy fields. Ultimately, a structured and detailed MRI report enables radiologists to function as key contributors within the multidisciplinary sarcoma team. By systematically describing tumor morphology, extent, and biologic behavior, radiologists help optimize biopsy targeting, surgical planning, and long-term surveillance strategies for patients with soft-tissue tumors. APA Citation (7th Edition) Riley, G. M., Steffner, R., Kwong, S., Chin, A., & Boutin, R. D. (2024). MRI of soft-tissue tumors: What to include in the report. RadioGraphics, 44(6). Radiological Society of North America. Hashtags: #OrthopedicOncology #SoftTissueSarcoma #Radiology #MRI #LimbSalvage #CancerSurgery #SurgicalPlanning #MedicalDeepDive #MusculoskeletalRadiology #OncologicImaging #RadiologyEducation #ImagingGuidelines #RSNA © 2025 AI Chavelle™ by Jeffrey Chen / SmartRad AI. All rights reserved.