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One of the most common misdiagnoses given to adults with ADHD is Bipolar Disorder (BD). This is often due to practitioners having far more knowledge of BD and far less knowledge of ADHD and their differential diagnosis. Yet, these disorders can also coexist; more often in the case of people with BD also having ADHD than vice versa. In this three-part series of videos, I discuss the overlap of ADHD with bipolar disorder, give some tips on differential diagnosis, and highlight some key issues n the management of this comorbid condition. Part 1 describes the overlap in the symptoms of both disorders that can often lead to confusion and even misdiagnosis of ADHD as being bipolar disorder, when it is not. However, the two disorders can coexist in a minority of cases of each. Here I discuss how one might distinguish the symptoms of ADHD that overlap with the BD symptom list, emphasizing the more extreme and episodic nature of these symptoms when they occur in BD. In Part 2, I discuss the percentage of overlap between the two disorders, and explain that the degree of comorbidity is often age-related. I also point out some differential diagnostic tips in distinguishing the two disorders. In Part 3, I describe some basic issues involved in the management of the disorders when they co-exist. References: Meta-analysis of personal and familial co-occurrence of Attention Deficit/Hyperactivity Disorder and Bipolar Disorder E Khoury, E Acquaviva, D Purper-Ouakil… - Neuroscience & Biobehavioral Reviews, 2023, 146. https://doi.org/10.1016/j.neubiorev.2... Comorbidity of ADHD and adult bipolar disorder: A systematic review and meta-analysis C Schiweck, G Arteaga-Henriquez, M Aichholzer… - Neuroscience & Biobehavioral Reviews, 2021, 124, pp. 100-123. https://doi.org/10.1016/j.neubiorev.2... ADHD and bipolar disorder in adulthood: clinical and treatment implications V Salvi, E Ribuoli, M Servasi, L Orsolini, U Volpe - Medicina, 2021, 57(5), 466. https://doi.org/10.3390/medicina57050466 Development of bipolar disorder in patients with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis of prospective studies GE Brancati, G Perugi, A Milone, G Masi… Journal of Affective Disorders, 2021 https://doi.org/10.1016/j.jad.2021.06... Differentiation and comorbidity of bipolar disorder and attention deficit and hyperactivity disorder in children, adolescents, and adults: A clinical and nosological … A Comparelli, L Polidori, G Sarli, A Pistollato… - Frontiers in Psychiatry, 2022, 13, https://doi.org/10.3389/fpsyt.2022.94... Attention deficit hyperactivity disorder and bipolar disorder: diagnosis, treatments, and clinical considerations: a narrative review AN Edinoff, TL Apgar, JJ Rogers, JD Harper… - Psychiatry International, 2021, 3(1), 17-28. https://doi.org/10.3390/psychiatryint... Clinical correlates of comorbid attention deficit hyperactivity disorder in adults suffering from bipolar disorder: a meta-analysis F Bartoli, T Callovini, D Cavaleri… - Australian & New Zealand Journal of Psychiatry, 2023, 57(1). https://doi.org/10.1177/0004867422110... Clinical and genetic correlates of bipolar disorder with childhood-onset attention deficit disorder NA Nunez, BJ Coombes, F Romo-Nava… - Frontiers in Psychiatry, 2022, 13. https://doi.org/10.3389/fpsyt.2022.88...