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Copyright: Intra-Lock International L-PRF™ is a 3-D autogenous combination of Platelet Rich Fibrin derived from the patient’s blood. A simplified chairside procedure results in the production of a thin, compressed layer of platelet rich fibrin that is strong, pliable and suitable for suturing. This natural fibrin network is rich in platelets, growth factors and cytokines that are derived from the blood platelets and leukocytes. The presences of these proteins have been reported to produce rapid healing, especially during the critical first seven days after placement. This network promotes more efficient cell migration and proliferation without chemical or bovine thrombin additives. L-PRF centrifuge (IntraSpin) from Intra-Lock is the only CE and FDA cleared system for the preparation of L-PRF. Clinically, Leukocyte-Platelet Rich Fibrin displays excellent working properties. This biomaterial is resilient, strong and pliable, making it easy to manipulate. It can be cut to size, and is supple enough to adapt to many anatomical areas. It is adhesive in nature and very receptive to suturing. In addition, there is ample working time since L-PRF™ is stable at room temperature for several hours. Applications in Dental /oral and Maxillofacial surgical sites: Bone defects Extraction sockets Sinus and dental ridge augmentation Palatal defects Maxillary bone atrophy