Скачать с ютуб 乳腺癌靶向药物副作用有哪些 景娜 山西省肿瘤医院 в хорошем качестве

乳腺癌靶向药物副作用有哪些 景娜 山西省肿瘤医院

乳腺癌靶向药物副作用有哪些 景娜 山西省肿瘤医院 乳腺癌靶向药物有曲妥珠单抗、帕托珠单抗及吡咯替尼小分子靶向TKI的靶向药物，其副作用有哪些？曲妥珠单抗最为要的不良反应是破坏心脏有效泵血能力，有时会起到轻度的心脏衰竭，包括产生呼吸急促和心痛表现，在曲妥珠单抗用药期间，每间隔三个月要检测心功能，做心脏超声检查，严密监测心脏功能情况。若出现心脏功能下降，女性必须中断或停止治疗。另外，还有一些其他的副作用，比如消化系统方面会出现厌食、便秘、腹泻、消化不良、胃肠胀气、呕吐恶心等症状，在神经系统方面会有焦虑、抑郁、眩晕、失眠、异常嗜睡等症状。在呼吸系统也会出现类似哮喘、咳嗽增多、呼吸困难、鼻出血、胸腔积液、咽炎等。但这些症状在临床中是特别少见的，患者不必太担心。另外，靶向二线药物的选择，比如吡咯替尼、拉帕替尼、阿法替尼等小分子TKI类的口服药物的靶向药物最常见的副作用是腹泻等胃肠的胃肠道症状。 What are the side effects of targeted drugs for breast cancer The targeted drugs for breast cancer include trastuzumab, patorzumab and small molecules of pyrrolidine targeting TKI, What are the side effects? The most important side effect of trastuzumab is to destroy the effective pumping capacity of the heart, Sometimes it has mild heart failure, This includes shortness of breath and heartache, During trastuzumab administration, Heart function should be tested every three months, Do a heart ultrasound, Closely monitor the heart function. If there is a decrease in heart function, Women must discontinue or discontinue treatment. In addition, There are other side effects, For example, there will be anorexia, constipation, diarrhea, dyspepsia, flatulence, vomiting and nausea in the digestive system, In the nervous system, there will be anxiety, depression, dizziness, insomnia, abnormal sleepiness and other symptoms. In the respiratory system, there will be asthma, cough, dyspnea, epistaxis, pleural effusion, pharyngitis and so on. But these symptoms are very rare in clinic, Patients don't have to worry too much. In addition, Selection of targeted second-line drugs, For example, the most common side effect of small molecule TKI drugs such as pyrrolidine, lapatinib and afatinib is gastrointestinal symptoms such as diarrhea.