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Authors: Sushko, Vadim*; Zhang, Dan; Gall, Jürgen; Khoreva, Anna Description: Joint synthesis of images and segmentation masks with generative adversarial networks (GANs) is promising to reduce the effort needed for collecting image data with pixel-wise annotations. However, to learn high-fidelity image-mask synthesis, existing GAN approaches first need a pre-training phase requiring large amounts of image data, which limits their utilization in restricted image domains. In this work, we take a step to reduce this limitation, introducing the task of one-shot image-mask synthesis. We aim to generate diverse images and their segmentation masks given only a single labelled example, and assuming, contrary to previous models, no access to any pre-training data. To this end, inspired by the recent architectural developments of single-image GANs, we introduce our OSMIS model which enables the synthesis of segmentation masks that are precisely aligned to the generated images in the one-shot regime. Besides achieving the high fidelity of generated masks, OSMIS outperforms state-of-the-art single-image GAN models in image synthesis quality and diversity. In addition, despite not using any additional data, OSMIS demonstrates an impressive ability to serve as a source of useful data augmentation for one-shot segmentation applications, providing performance gains that are complementary to standard data augmentation techniques. Code is available at https://github.com/boschresearch/one-....