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Dr. Sherman J. Silber (Infertility Center of St. Louis) hosts Rajeev & Zakiya, a Wisconsin couple who conceived after multiple failed, high-dose IVF cycles elsewhere. Other clinics pushed routine “genetic testing” (chromosome counting) that labeled every embryo “abnormal” and recommended donor eggs. With mini-IVF at our center—low-dose meds, routine ICSI, day-3 freezing, and a freeze-then-transfer approach—they created 4 mature eggs → 4 embryos, and a frozen embryo transfer led to their daughter, Hope. The couple highlights simpler meds, fewer visits, fast and clear lab updates, and a highly organized care team. What You’ll Learn • Why mini-IVF beats high-dose stimulation for egg quality—especially over 40 • Our stance on routine embryo “genetic testing” (PGT-A) and why it can mislabel embryos • Day-3 vs. blast: higher baby-per-egg efficiency with day-3 banking, then transfer later • Vitrification done right (training with Japanese masters) = zero-damage freezing/thawing • Medication plan: tiny FSH doses every other day + clomiphene; HCG trigger; minimal antagonists • Prep: simple birth-control synchronization; 4–6 days of local monitoring before retrieval • Low ovarian reserve: why mini-IVF is the only sensible approach • Transparent fees: set pricing includes freezing, storage, thawing; ICSI & assisted hatching included • Real numbers: ~60% per transfer in younger patients; banking boosts overall live-birth odds Key Moments 00:00 Intro & call-in info 02:05 Three failed high-dose cycles elsewhere; “all embryos abnormal” 07:10 Finding mini-IVF; dropping unnecessary testing 10:40 Simple meds: one shot q.o.d. + pill; immediate lab updates 14:20 Why day-3 freeze-all improves baby-per-egg 18:30 Vitrification mastery & Japan collaboration 22:00 Q&A: age 34 outcomes, low ovarian reserve, costs, prep 29:30 Closing & free consult invitation Contact / Free Consult 📞 +1 314-576-1400 • 📧 [email protected] • 🌐 infertile.com