Risk of B-Cell Depleters Long-Term (Ocrevus, Rituximab, Kesimpta, Briumvi) скачать в хорошем качестве

Risk of B-Cell Depleters Long-Term (Ocrevus, Rituximab, Kesimpta, Briumvi)

Is it safe to take B-cell depleting medications for multiple sclerosis such as Ocrevus, Rituximab, Kesimpta, and Briumvi continuously for many years? In this video, I explain the immune system can become weaker over time with continuous use, and low immunoglobin (antibody) levels can result in serious infections. Notes: Is rituximab 500mg just as good as rituximab 1000mg for MS? This deescalation study suggests that decreasing the dose to 500mg does not affect clinical, MRI, or serum NfL results over a 12 month period and may be safer. https://pubmed.ncbi.nlm.nih.gov/32840... Do you really need Ocrevus every 6 months? This study in Italy during the pandemic found that "extended interval dosing" was linked to more MRI activity but not disability progression or NEDA-3. https://pubmed.ncbi.nlm.nih.gov/36036... What happens if you delay Ocrevus due to fear of covid? Nothing! This retrospective study suggests that extended interval dosing compared to standard dosing did not significantly change relapses, disability progression, MRI activity. https://pubmed.ncbi.nlm.nih.gov/34261... An extended dosing interval for rituximab for patients with stable MS during the COVID-19 pandemic may be associated with a low risk of disease activity. https://nn.neurology.org/content/7/5/... Living life without B cells: is repeated B-cell depletion a safe and effective long-term treatment plan for rheumatoid arthritis? https://www.ncbi.nlm.nih.gov/pmc/arti... Comment or ask questions below! I would be happy to answer! Subscribe on YouTube for more videos every Wednesday! Make video requests in the comments section! Check out my book “Resilience in the Face of Multiple Sclerosis” FREE on Amazon: https://amazon.com/dp/B07WP7H5LK It's about 5 people with MS who live incredible lives, the science and psychology of resilience, mindfulness, and ho’oponopono. Paperback priced to generate $0 royalty. Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research. Follow me on twitter:   / brandon_beaber   Music: INNER GRACE - Copyright 2018 Wilton Vought Source: Really Really Free Music Link:    • Видео   T he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.