Prevention of recurrent idiopathic gastroduodenal ulcer bleeding скачать в хорошем качестве

Prevention of recurrent idiopathic gastroduodenal ulcer bleeding

To cite: Wong GLH, Lau LHS, Ching JYL, et al. Gut 2020;69:652-657. Read the full article here: http://dx.doi.org/10.1136/gutjnl-2019... Objective: Patients with a history of Helicobacter pylori-negative idiopathic bleeding ulcers have a considerable risk of recurrent ulcer complications. We hypothesised that a proton pump inhibitor (lansoprazole) is superior to a histamine 2 receptor antagonist (famotidine) for the prevention of recurrent ulcer bleeding in such patients. Conclusions: This 2-year, double-blind randomised trial showed that among patients with a history of H. pylori-negative idiopathic ulcer bleeding, recurrent bleeding rates were comparable between users of lansoprazole and famotidine, although a small difference in efficacy cannot be excluded.