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This video discusses the topic of the role of abnormal kidney development in Chronic Kidney Disease (CKD). We define CKD, the symptomatology, and discuss how it is diagnosed. This video also touches on the different possible causes for chronic kidney disease, the anatomical abnormalities leading to its development, and possible treatment options. This video was made by McMaster students Pukhraj Gaheer, Sabhat Khan, and Hani Fakhri in collaboration with the McMaster Demystifying Medicine Program. Narrated by: Pukhraj Gaheer Subscribe to the McMaster Demystifying Medicine YouTube channel: / demystifyingmedicine . This video is provided for general and educational information only. Please consult your health care provider for Information about your health Copyright McMaster University 2022 #DemystifyingMedicine #KidneyDisease References: Black, M. J., Sutherland, M. R., Gubhaju, L., Kent, A. L., Dahlstrom, J. E., & Moore, L. (2013). When birth comes early: Effects on nephrogenesis. Nephrology, 18(3), 180–182. https://doi.org/10.1111/nep.12028 Denic, A., Glassock, R. J., & Rule, A. D. (2016). Structural and functional changes with the aging kidney. Advances in Chronic Kidney Disease, 23(1), 19–28. https://doi.org/10.1053/j.ackd.2015.0... Detecting kidney and urinary tract abnormalities before birth. National Kidney Foundation. (2017, February 3). Retrieved March 14, 2022, from https://www.kidney.org/atoz/content/d... Facts about chronic kidney disease. National Kidney Foundation. (2022, January 3). Retrieved March 14, 2022, from https://www.kidney.org/atoz/content/a... The impact of kidney development on the life course: A consensus document for action. (2017). Nephron, 136(1), 3–49. https://doi.org/10.1159/000457967 Mayo Foundation for Medical Education and Research. (2021, September 3). Chronic kidney disease. Mayo Clinic. Retrieved March 14, 2022, from https://www.mayoclinic.org/diseases-c... Rabinowitz, R., & Cubillos, J. (2022, February 22). Renal anomalies - pediatrics. Merck Manuals Professional Edition. Retrieved March 14, 2022, from https://www.merckmanuals.com/en-ca/pr...