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COVID-19 had a significant impact on the lives of many, and society is gradually moving past the pandemic. With the recent word that Boston University researchers conducted possible “gain of function” research and created a “dangerous” variant of SARS-CoV-2 with an 80% kill rate in mice, news and social media were quick to jump in onto the story, spreading concern to the public. This video will aim to go beyond sensationalized news headlines and break down the study in question. We will try to shed light on the multiple perspectives on the matter, perspectives on different sides of the topic and why this study may or may not be problematic. Finally, we seek to use this case as an opportunity to highlight the importance of ethics, safety, and communication in research. Disclaimer: We are not medical or health professionals, nor we are expert researchers. The information, statements, and comments in this video are strictly for educational purposes with the goal to promote people to engage in critical thinking when digesting new information. Music Bensound: "Elevate" - Motivational Royalty Free Music "AERØHEAD - Fragments" is under a Creative Commons (CC BY-SA 3.0) license / aer%c3%98head Timestamps: Introduction: 0:00-0:39 What does SARS-CoV-2 stand for?: 0:40-0:55 What is a virus and how does it replicate?: 0:55-1:37 What is a coronavirus and SARS-CoV-2?: 1:32-3:00 About the research study: 3:00-3:49 What is a chimeric virus?: 3:50-4:05 Results of the research study: 4:06-4:54 What is gain of function research?: 4:55-5:41 Was this study gain of function research: 5:42-6:20 Media Sensationalism: 6:21-6:37 Other points of criticism on the study and more: 6:38-7:03 Controversial research + Project MK Ultra example: 7:04-7:44 Ethics in research | overview + brief history: 7:45-8:30 Requisites and approval for Chimera study: 8:31-8:58 Missed communication w/NIAID: 8:59-9:17 Why is it important for us to have ethics in research?: 9:18-10:30 Should scientists have engineered this virus?: 10:31-11:12 This video was made by McMaster University students Charles Cai, Vithuyan Sugumar, and Ashley Tsoi in collaboration with the Demystifying Research McMaster Program. Copyright McMaster University 2023. #chimera, #gainoffunction, #research, #ethics References: https://pubmed.ncbi.nlm.nih.gov/32446... https://www.hopkinsguides.com/hopkins... Coronavirus_COVID_19__SARS_CoV_2_ https://febs.onlinelibrary.wiley.com/... Bacon, S. (1620). Novum Organum. P. F. Collier • NEIDL: Biosafety Level 4 https://www.bu.edu/researchsupport/co... https://www.statnews.com/2022/10/18/b... • Boston University | BU | 4K Campus Drone Tour https://www.pnas.org/doi/10.1073/pnas... https://www.biorxiv.org/content/10.11... https://www.mdpi.com/1660-4601/17/19/... • Видео https://www.cancer.gov/publications/d... https://www.ncbi.nlm.nih.gov/books/NB... https://www.nature.com/scitable/defin... https://time.com/6225643/lab-made-cov... https://www.niehs.nih.gov/research/re... https://www.niehs.nih.gov/research/re... • Secret cemetery behind The Allan Memorial ... https://consteril.com/biosafety-level... https://www.nytimes.com/packages/pdf/... https://www.who.int/activities/ensuri...