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Ripal Gandhi, MD, FSIR, FSVM (Miami Cardiac & Vascular Institute, Miami Cancer Institute) presents the clinical case of a 77-year-old female with hepatocellular carcinoma who underwent Y90 radioembolization using the TriNav® Infusion System. During the treatment procedure there was an iatrogenic complication involving dissection of the superior mesenteric artery and replaced right hepatic artery, but the TriNav Infusion System allowed for safe Y90 delivery to the target tumor thanks to its reflux protection properties. Post-treatment SPECT/CT imaging showed improved tumor perfusion compared to the standard microcatheter that was used in the mapping procedure, which demonstrates how TriNav can be used to effectively deliver Y90, even in a complicated case. To learn more about the TriNav Infusion System, visit https://trinavinfusion.com TriNav Description The TriNav Infusion System is a 0.021-inch lumen microcatheter with SmartValve™ self-expanding tip. SmartValve supports pressure generation, which enables delivery of therapeutic agents to selected sites in the peripheral vascular system. [1,3-5] Intended Use The TriNav Infusion System is intended for use in angiographic procedures. It delivers radiopaque media and therapeutic agents to selected sites in the peripheral vascular system.[2] Contraindications TriNav is not intended for use in the vasculature of the central nervous system (including the neurovasculature) or central circulatory system (including the coronary vasculature).[2] Rx Only. For the safe and proper use of the TriNav device, refer to the Instructions for Use. [1] Titano JJ, et al. Cardiovasc Intervent Radiol. 2019;42:560-568. [2] TriSalus™ TriNav™ Infusion System, Instructions for Use. [3] Kim AY, et al. PLoS One. 2017;12(9):e0183861. DOI: 10.1371/journal.pone.0183861. [4] Pasciak AS, et al. J Vasc Interv Radiol. 2015;26:660-669. [5] Durham E, Jaroch D, Hunter K. Poster presented at: World Conference on Interventional Oncology (WCIO); May 6-9, 2015; New York, NY.