神经内分泌肿瘤有哪些分类 高峻 山西省肿瘤医院 скачать в хорошем качестве

神经内分泌肿瘤有哪些分类 高峻 山西省肿瘤医院

神经内分泌肿瘤有哪些分类 高峻 山西省肿瘤医院 神经内分泌肿瘤是一大类疾病的总称，是指起源于全身任何部位的神经内分泌细胞的良恶性肿瘤。按照神经内分泌肿瘤细胞可以产生和分泌多种激素的部位分类，包括胰腺神经内分泌肿瘤、胃肠道的神经内分泌肿瘤肺、胸腺神经内分泌肿瘤、肾上腺肿瘤、嗜铬细胞瘤、副神经节瘤等等根据是否分泌激素和引起它的临床表现可分为功能性和无功能性的神经内分泌肿瘤两大类。功能性神经内分泌肿瘤表现为肿瘤释放过多的激素、引起各种临床综合征我们称之为类癌综合征。比如说胃泌素瘤引起卓-艾综合征，胰岛素瘤引起的低血糖综合征，血管活性肠肽瘤引起WDHA综合征。无功能性的神经内分泌肿瘤它们不产生激素，因此不伴有特征性的激素综合征，基于肿瘤的分化程度和分级进行分类，神经内分泌肿瘤的组织学分类对治疗决策及预后的判断非常重要。 Classification of neuroendocrine tumors Neuroendocrine tumor is a general term for a large class of diseases, It refers to the benign and malignant tumors originated from neuroendocrine cells in any part of the body. According to the location where neuroendocrine tumor cells can produce and secrete multiple hormones, It includes pancreatic neuroendocrine tumor, gastrointestinal neuroendocrine tumor, lung, thymus neuroendocrine tumor, adrenal tumor, pheochromocytoma, paraganglioma, etc. according to whether or not they secrete hormones and the clinical manifestations, they can be divided into functional and non functional neuroendocrine tumors. Functional neuroendocrine tumors are characterized by the release of too many hormones, causing a variety of clinical syndromes, which we call carcinoid syndrome. For example, gastrinoma causes Zhuo AI syndrome, Hypoglycemia syndrome caused by insulinoma, Vasoactive enteropeptidoma causes wdha syndrome. They don't produce hormones, Therefore, there is no characteristic hormone syndrome, Classification is based on the degree and grade of tumor differentiation, The histological classification of neuroendocrine tumors is very important for treatment decision and prognosis.