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Introduction and Indications for Nerve Transfers Authors: Mackinnon SE1, Yee A1 Published: May 7, 2016 AUTHOR INFORMATION 1Division of Plastic and Reconstructive Surgery, Washington University, St. Louis, Missouri DISCLOSURE No authors have a financial interest in any of the products, devices, or drugs mentioned in this production or publication. ABSTRACT This presentation is an introduction to nerve transfers and details the indications for performing these procedures. Experimental studies are discussed in respect to nerve injury and recovery and the window for reinnervation. The classification for nerve injuries is also reviewed with an additional category that distinguishes recovery to either favorable (I, II, III degree) or unfavorable (IV, V degree). Nerve transfers are performed for unfavorable nerve injuries and the associated indications are provided within this presentation. Factors for poor functional recovery are also discussed to optimize outcomes following nerve transfers. TABLE OF CONTENTS 00:00 Introduction 00:10 Nerve Injury and Recovery 01:06 Factors for Window of Reinnervation and Functional Recovery 02:25 Experimental Study for Percent of Denervation for Functional Loss 03:51 Regenerative Rate of Peripheral Nerves 06:01 Factors for Poor Functional Recovery 06:51 Classification of Nerve Injuries 07:15 Favorable and Unfavorable Classification for Recovery 07:48 Indications for Nerve Transfers 08:53 Mantra for Nerve Transfers: Donor Distal Recipient Proximal 09:26 Indications for Supercharge Nerve Transfers 10:44 Indications for Supercharge Nerve Transfer for Ulnar Nerve Injuries 13:07 Conclusion