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NSCLC highlights from ASCO 2021

Heather A. Wakelee, MD, Stanford University, Stanford, CA, discusses non-small cell lung cancer (NSCLC) highlights from the American Society of Clinical Oncology (ASCO) 2021 Virtual Meeting, including the results of a FDA analysis, looking across metastatic NSCLC trials of patients with 1-49% PD-L1 expression; chemotherapy and immunotherapy in combination was found to be more effective than immunotherapy alone. In addition, data was presented concerning EGFR TKI osimertinib in EGFR mutated NSCLC; results were consistent with previous research, with disease-free survival (DFS) benefit but no overall survival (OS) benefit. Future research may focus on determining the optimal strategy for early-stage patients, considering screening for salient biomarkers, such as EGFR and PD-L1. This interview took place at the American Society of Clinical Oncology (ASCO) 2021 Virtual Meeting.

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