IgA-NP: Treatment Standard & Future Perspective - Prof. Jonathan Barratt, Prof. Jai Radhakrishnan скачать в хорошем качестве

IgA-NP: Treatment Standard & Future Perspective - Prof. Jonathan Barratt, Prof. Jai Radhakrishnan

Prof. Jai Radhakrishnan (New York City, NY, USA) and Prof. Jonathan Barratt (Leicester, United Kingdom) discuss current standards and future outlooks for the treatment of Immunoglobulin A Nephropathy (IgAN), focussing upon the KDIGO 2025 Clinical Practice Guideline for the Management of IgAN and Immunoglobulin A Vasculitis (IgAV). Prof. Radhakrishnan and Prof. Barratt have recently published an Editorial and Treatment Standard paper, respectively, on IgAN, which has been picked by the journal's Editor-in-Chief Dr. Hans-Joachim Anders and by MARKUS @ HOMe Editors as our “NDT's Papers of the Month”. Dr. Barratt is the Mayer Professor of Renal Medicine at the University of Leicester, UK. He leads the Renal Research Group within the College of Life Sciences University of Leicester and the IgA nephropathy Rare Disease Group for the UK National Registry of Rare Kidney Diseases (RaDaR). Dr. Radhakrishnan is Professor of Medicine at Columbia University Medical Center and Director of Clinical Services of the Nephrology Division. Additionally, he is a co-director of the hypertension center of Columbia University. The interview was recorded on 13th October, 2025. Moderators: Prof. Dr. Andreas Kronbichler (Innsbruck, Austria) and Prof. Dr. Gunnar Heine (Frankfurt am Main, Germany). Articles discussed: IgA nephropathy in adults-treatment standard. Gleeson PJ, O'Shaughnessy MM, Barratt J Nephrol Dial Transplant 2023 doi: 10.1093/ndt/gfad146 Active glomerular inflammation versus chronicity and fibrosis: the role of targeted therapies in IgA nephropathy. Radhakrishnan J, Lafayette RA Nephrol Dial Transplant 2025 doi: 10.1093/ndt/gfaf059 Antiproteinuric effect of SGLT2 inhibitors in non-diabetic glomerulopathies is dependent on body mass index. Vargas-Brochero MJ, Russo I, Mazzierli T, Cara A, Berti GM, Milheiro J, Thongprayoon C, Allinovi M, Somma C, Raglianti V, D'Arpino E, Zand L, Nuñez S, Soler MJ, Sethi S, Gutiérrez E, Praga M, Caravaca-Fontan F, Romagnani P, Fervenza FC Nephrol Dial Transplant 2025 doi: 10.1093/ndt/gfaf197 KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV). Kidney Disease: Improving Global Outcomes (KDIGO) IgAN and IgAV Work Group; Rovin BH, Barratt J, Cook HT, Noronha IL, Reich HN, Suzuki Y, Tang SCW, Trimarch H, Floege J. Kidney Int 2025 doi: 10.1016/j.kint.2025.04.004 Albuminuria predicts kidney events in IgA nephropathy. Faucon AL, Lundberg S, Lando S, Wijkström J, Segelmark M, Evans M, Carrero JJ Nephrol Dial Transplant 2025 doi: 10.1093/ndt/gfae085