Females With AR Exhibit Lower Mortality LVESVi Thresholds, With Nina Marsan, MD, and Pilar Santi, MD скачать в хорошем качестве

Females With AR Exhibit Lower Mortality LVESVi Thresholds, With Nina Marsan, MD, and Pilar Santi, MD

Female patients with moderate-to-severe aortic regurgitation (AR) exhibit worse survival during medical management due to lower mortality thresholds for left ventricular end-systolic volume index (LVESVi) in women than in men, according to a recent study. Because LV dilatation is a strong indicator of adverse outcomes in patients with AR, current guidelines recommend using LV end-systolic diameter index (LVESDi) as a criterion for aortic valve surgery (AVS). However, other studies have indicated that LVESVi may depict adverse LV remodeling better than LVESDi, serving as a more effective predictor of heart failure, mortality, and survival. The 2025 European guidelines recognize LVESVi as an alternative criterion for AVS; however, the recommendation includes the same threshold for men and women. Now, in an interview with Pilar Santi, MD, and Nina Marsan, MD, from Leiden University Medical Center, we discuss why future guidelines should reflect this disparity between male and female patients with AR. Read the full article here: https://www.hcplive.com/view/female-p... Key Timestamps 00:00:01 Intro 00:00:10 Study overview 00:06:15 Earlier AVS intervention 00:07:22 LVESVi as a routine aspect of surveillance 00:08:15 Getting sex-specific cutoffs in guidelines #cardiology #surgery