Streptomycin: The Controversy over the First Tuberculosis Antibiotic (Schatz vs Waksman) скачать в хорошем качестве

Streptomycin: The Controversy over the First Tuberculosis Antibiotic (Schatz vs Waksman)

Streptomycin was the first effective antibiotic against tuberculosis. But it’s discovery was controversial. The credit was awarded mostly to Selman Waksman, but his graduate student, Albert Schatz, had a legitimate claim to the title. In this video, you’ll learn why penicillin doesn’t work on tuberculosis, the discovery story of streptomycin, the pharmacology of aminoglycoside antibiotics, and why there’s so much controvery over the Nobel Prize of 1952. ☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️ 🔗 L I N K S 🔗 📱Instagram:   / patkellyteaches   🐦Twitter:   / patkellyteaches   💰Patreon:   / corporis   🔬Main channel:    / corporis   📚My favorite books https://docs.google.com/document/d/1w... 🔑 P A T R O N S 🔑 Joanne K Sal F. Ansel K Anton Brandon K Pranav M Paul Brendan P Dane M Kristoffer R Jakub V Joe B Karly N Mindi F Drake W Kathy K Mike W Hyeon-Seo Jacob S. Robin B Robb W Sarah B Carl Dontae W Karen S Michael R Brian H Jonathan G Brian T Waffles the Dog Thelma S Silverstar Brian B Michael G Zoe C 📜 S O U R C E S 📜 Miracle Cure, the Creation of Antibiotics https://www.amazon.com/Miracle-Cure-C... Tuberculosis (2023) https://www.ncbi.nlm.nih.gov/books/NB... Immune evasion and provocation by Mycobacterium tuberculosis (2022) https://www.nature.com/articles/s4157... Tuberculosis in Adults and Children (2015) https://www.ncbi.nlm.nih.gov/books/NB... The mycobacterial cell wall (2015) https://www.ncbi.nlm.nih.gov/pmc/arti... Interplay of human macrophages and mycobacterium tuberculosis https://www.researchgate.net/publicat... Antibiotic antagonist: the curious career of René Dubos (2016) https://www.ncbi.nlm.nih.gov/pmc/arti... Dubos and Avery enzyme (1931) https://www.ncbi.nlm.nih.gov/pmc/arti... Dubos antibiotic 1 (1939) https://rupress.org/jem/article-pdf/7... Dubos antibiotic 2 (1939) https://rupress.org/jem/article-pdf/7... Dubos antibiotic 3 (1939) https://rupress.org/jem/article-pdf/7... Dubos 1941 https://rupress.org/jem/article-pdf/7... Gramicidin pharmacology https://www.ncbi.nlm.nih.gov/pmc/arti... Russian Gramicidin https://link.springer.com/content/pdf... Waksman and Woodruff, antinomyces antibioticus (1941) https://www.ncbi.nlm.nih.gov/pmc/arti... Chemical nature of actinomycin (1941) https://pdf.sciencedirectassets.com/7... Streptothricin paper (1942) https://journals.sagepub.com/doi/abs/... Fumigacin and Clavacin (1942) https://journals.asm.org/doi/pdf/10.1... Antibioic roundup! (1942) https://journals.asm.org/doi/10.1128/... The renaming of actinomycetes to streptomycetes https://www.ncbi.nlm.nih.gov/pmc/arti... Streptomycin original paper (1944) https://journals.sagepub.com/doi/abs/... Mayo Clinic human TB paper (1945) https://www.cabdirect.org/cabdirect/a... Streptomycin patent https://patentimages.storage.googleap... Waksman Nobel speech (1952) https://www.nobelprize.org/uploads/20... Streptomycin: Discovery and Resultant Controversy (1991) https://www.jstor.org/stable/23330620 Streptomycin, Schatz v. Waksman, and the Balance of Credit for Discovery (2004) https://www.jstor.org/stable/24632177 Streptomycin https://www.ncbi.nlm.nih.gov/books/NB... Aminoglycosides https://www.ncbi.nlm.nih.gov/pmc/arti... Aminoglycoside Revival: Review of a Historically Important Class of Antimicrobials Undergoing Rejuvenation https://journals.asm.org/doi/10.1128/... Double blinding, explained https://www.ncbi.nlm.nih.gov/books/NB... Lehmann and PAS https://www.ncbi.nlm.nih.gov/pmc/arti... 🖼 Image attributions exceeded YouTube’s character limit! Please find attributions on the annotated script here:   / streptomycin-93092791   0:00 Intro 0:38 Part 1: The Problem with Penicillin 5:36 Part 2: Patents and Promises 15:28 Part 3: Schatz hits the Fan 20:31 Coda: Impact of Streptomycin