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#ThermalBurns #BurnCare #HyperbaricOxygenTherapy #HBOT #AdjunctiveTherapy #ZoneOfStasis #WoundHealing #TissueOxygenation #Edema #InfectionControl #PainManagement #CostSavings #BurnRecovery #CriticalCare #Surgery #SkinGrafting #MedicalInnovation #Healthcare Thermal burns are complex, dynamic injuries with damage evolving for days, causing fluid loss, swelling (edema), and vessel damage, creating a hostile environment. The "zone of stasis" is a critical area of injured, potentially salvageable tissue. Burn care challenges include high mortality, long stays, infection, pain, and cost. Adjunctive Hyperbaric Oxygen Therapy (HBOT), used with standard care, involves breathing pure oxygen under pressure. This forces more oxygen into plasma, delivering it to struggling tissues like the zone of stasis. HBOT may aid tissue survival, potentially preventing burns from deepening, reduce swelling via vasoconstriction, improve circulation, boost infection control by enhancing white blood cell function and antibiotic effectiveness, accelerate wound healing, potentially reduce need for grafts/surgeries, help donor sites heal, and modulate pain. Evidence suggests potential benefits like reduced mortality, shorter hospital stays, fewer operations, lower costs, better tissue survival, and less pain. Despite substantial evidence, widespread adoption is challenged by the difficulty of large randomized controlled trials. HBOT addresses core burn issues: tissue oxygenation, swelling, and healing delays, offering potential for improved outcomes and cost savings.