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Watch the Full Video at https://www.jove.com/v/58454/assessin.... Assessing Neuroprotective Effects of Glycyrrhizae Radix et Rhizoma Extract Using a Transient Middle Cerebral Artery Occlusion Mouse Model - a 2 minute Preview of the Experimental Protocol Se-Eun Lee, Chiyeon Lim, Minji Lee, Chang-Hyun Kim, Hyungwoo Kim, Byoungho Lee, Suin Cho Pusan National University, School of Korean Medicine; Dongguk University, College of Medicine; Kyunghee Naseul Korean Medicine Clinic,; In this study, we modify an existing experimental method to obtain more reproducible results, by establishing a middle cerebral artery occlusion (MCAO) mouse model. Oral administration of Glycyrrhizae Radix et Rhizome (GR) methanol extract (GRex), following stroke induction, significantly decreased total infarction volume relative to the untreated control group. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments