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Cholera is an infectious disease that leads to an individual having severe watery diarrhea. If untreated, this disease may lead to dehydration and even death. Cholera is contracted by consuming food or water that is contaminated by the bacterium known as vibrio cholerae. This video provides general information about cholera, outlines the mechanism of the cholera toxin and provides prevention and treatment strategies. This video was made by McMaster Demystifying Medicine students: Aimen Shahzad, Amir Reihani, Quan Zhou and Youssef Zohdy. Copyright McMaster University 2020. References: Ali, M., Nelson, A. R., Lopez, A. L., & Sack, D. A. (2015). Updated Global Burden of Cholera in Endemic Countries. PLOS Neglected Tropical Diseases, 9 (6). DOI: 10.1371/journal.pntd.0003832 Bennett. V., Okeefe, E., & Cuatrecasas, P. (1975). Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions. Proceedings of the National Academy of Sciences, 72 (1), 33–37. DOI: 10.1073/pnas.72.1.33 World Health Organization (WHO). Cholera. (2019, January 17). Retrieved from https://www.who.int/news-room/fact-sh... Davies, H. G., Bowman, C., & Luby, S. P. (2017). Cholera – management and prevention. Journal of Infection, 74. DOI: 10.1016/s0163-4453(17)30194-9 Centers for Disease Control (CDC). Five Basic Cholera Prevention Steps. (2017, November 13). Retrieved from https://www.cdc.gov/cholera/preventio... Centers for Disease Control (CDC). Treatment. (2018, May 21). Retrieved from https://www.cdc.gov/cholera/treatment...