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Infective Endocarditis: Modified Duke Criteria

There are two major criteria for infective endocarditis. The first is a positive blood culture for endocarditis. This criteria is established in one of three ways; 1. If typical microorganisms consistent with IE are found on two separate blood cultures 2. If blood cultures are persistently positive 3. If a single blood culture is positive for Coxiella burnetii or a phase I IgG antibody titer is greater than 1:800 The second major criteria is evidence of endocardial involvement. This criteria is established in one of two ways; 1. If an echocardiogram detects a vegetation, an abscess, or a new partial dehiscence of a prosthetic valve. 2. If there is new valvular regurgitation. There are five minor criteria for endocarditis. 1. A predisposing factor such as iv drug use or a predisposing heart condition 2. Temperature greater than 38oC 3. Vascular phenomena such as a major arterial emboli, mycotic aneurysm and janeway lesions. 4. Immunologic phenomena such as osler nodes, roth spots, and positive rheumatoid factor. 5. Microbiologic evidence such as positive blood culture not meeting a major criterion or serologic evidence of an active infection with an organism known to cause infective endocarditis. A definite diagnosis of IE can be made with one of three combinations of the criteria mentioned: 1. Two major criteria 2. 1 major and 1 minor criteria 3. All 5 minor criteria The diagnosis is considered possible if 1 major and 1 minor criteria are met, or if there are 3 minor. The diagnosis is rejected if only 2 minor criteria or less are present. 🌐 Check out our website for more video lectures https://www.med4vl.com 📺 Subscribe To My Channel and Get More Great Quizzes and Tutorials    / @med4vl   Disclaimer: All the information provided by Medical Education for Visual Learners and associated videos are strictly for informational purposes only. It is not intended as a substitute for medical advice from your health care provider or physician. It should not be used to overrule the advice of a qualified healthcare provider, nor to provide advice for emergency medical treatment. If you think that you or someone that you know may be suffering from a medical condition, then please consult your physician or seek immediate medical attention.