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Practice and Prepare @ https://www.doorsteptutor.com/ Lectures on Various Subjects like Science, Social Studies and Humanities subscribe / testprep Examrace Lectures in Hindi subscribe / examracehindi For kids videos nursery to Class 5 subscribe / funprof For Science (Physics, Chemistry, Biology and Mathematics) Class 11-12 and important topics subscribe / doorsteptutor Also visit NCERT Solutions, NIOS @ https://www.flexiprep.com/ IGCSE, A & AS Level @ https://www.examtestprep.com/ Antibodies are glycoproteins, termed as immunoglobulins (Igs), which are produced in response to an immune reaction and specifically bind to antigens responsible for initiating the reaction. Antibodies, which are also called immunoglobulins (Ig), all have the same basic Y-shape, but there are five variations on this theme — called IgG, IgM, IgA, IgD and IgE Immunoglobulin G, or IgG, is just one Y, whereas IgM looks a bit like the 10-armed Hindu goddess Durga, with five Ys stacked together, and each prong can bind one antigen. IgG and IgM are the antibodies that circulate in the bloodstream and go into solid organs, Cyster said. IgA is "squirted out of the body," in mucus or secretions, Cyster told Live Science. IgE is the antibody that typically triggers allergic responses, such as to pollen or peanuts. IgD has historically been enigmatic, but one of its roles is to help activate the cells that make antibodies. IgG is the main component of the humoral immune system (immune response initiated by macromolecules present in the extracellular fluid) because of its abundance. Proteins are responsible for triggering IgG1 and IgG3 production, whereas IgG2 and IgG4 typically respond to foreign polysaccharides. Due to its small size (monomeric) and high diffusibility, IgG is the prevalent type in the extracellular fluid that binds Fc receptors on phagocytic or other lytic cells and initiates the antibody-dependent cell-mediated cytotoxicity (ADCC) response – a cell-mediated defense mechanism wherein effector cells (phagocytes) destroy the target cell IgG triggers phagocytosis to initiate opsonization reaction – a process used to destroy foreign particles (e.g. bacteria) through phagocytosis. Apart from these functions, IgG is the only antibody that can cross the placenta and provides passive immunity to the fetus and infants in the first few months of life. Chapters: 0:00 Antibody or Immunoglobulins 0:14 Antibody 4:30 Types of Antibodies 7:20 IgM 8:08 IgG 9:44 IgA 10:32 IgE 11:02 IgD 12:01 Camelid Antibodies #antibodyorimmunoglobulins #antibody #typesofantibodies #igm #igg #iga #ige #igd #camelidantibodies #examrace #examrace #upsc #ugcnet