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Alexander C. Stahn is Professor of Physiology in Extreme Environments at Charité – Universitätsmedizin Berlin. He is Deputy Director of the Institute of Physiology, and head of the working group “Space Medicine & Extreme Environments” at Charité. His research focuses on the effects of spaceflight and extreme environments on brain and behavior. Dr. Stahn is particularly interested in the role of social isolation, sensory deprivation and physical inactivity on the brain, for which he received several grants from NASA, ESA, and DLR. Some of his research on the effects of Antarctic expeditions on the brain ranks currently among the top 5% of all research outputs ever tracked by Altmetric. Current major projects include his contribution to the NASA CIPHER investigation, where he is identifying the dose-response relationships between spaceflight duration, brain changes and their molecular signatures. His recent work includes a cooperation with SpaceX to assess brain changes using EEG and MRI in response to short-duration spaceflight in civilian astronauts.