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This video presents a patient’s diagnosis and prognosis of deep vein thrombosis (DVT) and the molecular mechanisms including the symptoms involved in venous thrombosis. This video was made by McMaster Demystifying Medicine students: Celene Titus, Tanya Joseph, Diveena Tharmaseelan and Basil Bharoka. Copyright McMaster University 2020 References: Esmon C. Basic mechanisms and pathogenesis of venous thrombosis. Blood Reviews. 2009;23(5):225-229. DOI: 10.1016/j.blre.2009.07.002. Ganetsky M, Babu KM, Salhanick SD, Brown RS, Boyer EW. Dabigatran: A review of pharmacology and management of bleeding complications of this novel oral anticoagulant. Journal of Medical Toxicology. 2011 Dec 1;7(4):281-7. DOI: 10.1007/s13181-011-0178-y. Hyers, Thomas M., Giancarlo Agnelli, Russell D. Hull, Timothy A. Morris, Michel Samama, Victor Tapson, and John G. Weg. Antithrombotic therapy for venous thromboembolic disease. Chest 119, no. 1 (2001): 176S-193S. Dr. Matt & Dr. Mike's Medical Channel. Warfarin - Mechanism of Action. YouTube. July 27, 2017. • Warfarin - Mechanism of Action . Scarvelis, Dimitrios, and Philip S. Wells. Diagnosis and treatment of deep-vein thrombosis. Canadian Medical Association Journal. 175, no. 9 (2006): 1087-1092. Vitamin K-Dependent Protein. Science Direct.. https://www.sciencedirect.com/topics/.... Anderson FA, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, Forcier A, Dalen JE. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism: the Worcester DVT Study. Archives of Internal Medicine. 1991 May 1;151(5):933-8. Smith, S. A., Travers, R. J., & Morrissey, J. H. (2015). How it all starts: Initiation of the clotting cascade. Critical Reviews in Biochemistry and Molecular Biology, 50(4), 326-336. Martini, W. Z. (2016). Coagulation complications following trauma. Military Medical Research, 3(1). Bovill, E. G., & Vliet, A. V. D. (2011). Venous valvular stasis-associated hypoxia and thrombosis: What is the link? Annual Review of Physiology, 011;73:527-45. DOI: 10.1146/annurev-physiol-012110-142305. Mcever, R. (2002). P-selectin and PSGL-1: Exploiting Connections Between Inflammation and Venous Thrombosis. Thrombosis and Haemostasis, 87(03), 364-365. Thrombosis Adviser. Platelet Activation and Factors for Clot Formation. YouTube. • Platelet Activation and Factors for Clot F... Thrombosis Adviser. Coagulation Cascade Animation - Physiology of Hemostasis. YouTube. • Coagulation Cascade Animation - Physiology... American Society of Hematology. The Components of Blood and Their Importance. YouTube. • The Components of Blood and Their Importance