Thomas D. Wang – Video Comment on “Multimodal endoscope can quantify wide-field fluorescence...” скачать в хорошем качестве

Thomas D. Wang – Video Comment on “Multimodal endoscope can quantify wide-field fluorescence...”

Multimodal endoscope can quantify wide-field fluorescence detection of Barrett’s neoplasia Bishnu P. Joshi, Xiyu Duan, Richard S. Kwon, Cyrus Piraka, B. Joseph Elmunzer, Shaoying Lu, Emily F. Rabinsky, David G. Beer, Henry D. Appelman, Scott R. Owens, Rork Kuick, Nobuyuki Doguchi, D. Kim Turgeon, Thomas D. Wang Molecular endoscopy is an evolving technology for evaluation of preneoplastic lesions such as Barrett’s esophagus. In this study from the USA, the authors used a multimodal endoscope with a targeted fluorescent peptide for quantitative detection of neoplasia in 50 patients with Barrett’s esophagus. Early neoplasia was identified with 76% sensitivity, 94% specificity, and a positive predictive value of 96%. The authors conclude that a multimodal endoscope seems to offer an improved method for the early detection of neoplasia in the esophagus and other epithelial-derived cancers, which are often flat in appearance, patchy in distribution, and difficult to visualize with white-light endoscopy alone. Bibliography: DOI http://dx.doi.org/ 10.1055/s-0034-1392803 Published online: 1.10.2015 Endoscopy 2016; 48: 170–178 © Georg Thieme Verlag KG Stuttgart · New York ISSN 0013-726X