Impact of intravenous thrombolysis on different mechanical thrombectomy techniques скачать в хорошем качестве

Impact of intravenous thrombolysis on different mechanical thrombectomy techniques

The SWIFT-DIRECT trial (NCT03192332) assessed functional outcomes after acute ischemic stroke in patients who received intravenous thrombolysis plus mechanical thrombectomy (MT), compared to direct MT alone. MT alone was not found to be non-inferior to IVT+MT with regards to mRS scores at 90 days. Raoul Pop, MD, PhD, University Hospitals Strasbourg, University of Strasbourg, Strasbourg, France, shares the findings of a secondary analysis of SWFIT-DIRECT, focused on the influence of IVT on the efficacy of different first line mechanical thrombectomy techniques. In this data set, patients received MT with a stent retriever (SR), with or without additional use of a balloon guide catheter (BGC) and/or distal aspiration (DA) catheter. Each combination was assessed to see if the effect of IVT on the outcome varied across techniques. The results indicated no significant modification of the IVT+MT versus MT alone effect by the choice of first-line technique. However, the use of IVT was associated with significantly higher rates of first pass mTICI 2c-3 reperfusion. Additionally, SR+BGC was associated with a higher likelihood of achieving first pass mTICI 2c-3 reperfusion and functional independence and decreased odds of hemorrhagic transformation, compared to SR, and SR+DA. This interview took place during the European Stroke Organisation Conference (ESOC) in Munich, Germany. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.