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Video Summary: Neuroinflammation After Stroke - Understanding and Treating Post-Stroke Fatigue What This Video Covers: Post-stroke fatigue affects 50-70% of stroke survivors, leaving them with overwhelming exhaustion that can persist for years. This video explores the hidden culprit behind this debilitating condition: neuroinflammation in the brain. Key Topics Explained: The Inflammatory Response After Stroke How stroke triggers an immediate inflammatory cascade in the brain The role of microglia (the brain's immune cells) in both healing and ongoing damage Why inflammation sometimes becomes chronic instead of resolving M1 vs M2 Microglia: The Critical Balance M1 microglia: The "bad guys" that promote inflammation and tissue damage M2 microglia: The "good guys" that help repair and heal the brain How the balance between these two states determines recovery outcomes What Keeps Inflammation Going Poor sleep and disrupted circadian rhythms Oxidative stress and mitochondrial dysfunction Gut microbiome imbalances Chronic stress and depression Systemic infections Evidence-Based Solutions Covered: Sleep Optimization Sleep hygiene techniques Treatment of sleep apnea The critical role of quality sleep in reducing inflammation Powerful Polyphenols Resveratrol, curcumin, green tea extracts, and quercetin How these plant compounds shift microglia from M1 to M2 state Practical supplementation strategies Boosting Glutathione Why this "master antioxidant" is crucial for recovery N-acetylcysteine (NAC) supplementation Dietary approaches to enhance glutathione production Exercise and Movement How physical activity reduces neuroinflammation The optimal exercise prescription for stroke survivors Benefits of mind-body practices like tai chi and yoga Dietary Interventions The anti-inflammatory Mediterranean diet Potential benefits of intermittent fasting Foods that fight inflammation Why This Matters: Understanding neuroinflammation opens the door to targeted treatments that go beyond traditional stroke rehabilitation. By addressing the root cause of post-stroke fatigue, survivors can potentially improve their energy levels, cognitive function, and overall quality of life. This video provides evidence-based, actionable strategies that stroke survivors and their caregivers can discuss with healthcare providers to develop a comprehensive approach to managing post-stroke fatigue. P.S. Interested in the intensive training work we are doing and or tools we create for stroke survivors: visit https://www.stroke.rehab https://www.stroke.rehab https://www.brain.rehab (free portal) https://www.drarjankuipers.com (book a call) https://brainrehabfitness.com (shop for crawling machine and arm-swing walker, order now!)