Analyzing high concentration biologic therapeutic formulations скачать в хорошем качестве

Analyzing high concentration biologic therapeutic formulations

Developing high-dose biologic drugs for subcutaneous injection often requires high-concentration formulations. It also needs to optimize viscosity, solubility, and stability while overcoming analytical, manufacturing, and administration challenges. During this webinar, our presenters reflect on a set of surveys and discussions that took place within BioPhorum Development Group's Formulation workstream, as well as a paper published in the Journal of Pharmaceutical Sciences. Our speakers: Preeti Desai, Senior Principal Scientist, ‪@BristolMyersSquibb‬ Patrick Garidel, Head of TIP, ‪@boehringeringelheim‬ Francisca Gbormittah, Senior Manager, ‪@GSK‬ Douglas Kamen, Associate Director, ‪@Regeneron‬ Brittney Mills, Principal Research Scientist, ‪@AbbVie‬ Chakravarthy Nachu Narasimhan, Senior Principal Scientist, ‪@Merck‬ Shubhadra Singh, Scientific Leader, ‪@GSK‬ Elaine S.E. Stokes, lead Facilitator, BioPhorum Erika Walsh, Associate Principal Scientist, ‪@Merck‬ Chapters: 0:00 Webinar and BioPhorum introduction 6:09 Solubility 11:00 Viscosity 14:25 Stability 30:40 Sample preparation and analytical testing considerations 33:56 Technology for delivering large volume doses 37:49 Conclusions #BioPhorum #DevelopmentGroup #therapeutic #biological #biopharma #biopharmaceutics