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[00:00] Classification: A detailed breakdown of Type 1 (Insulin-Dependent) and Type 2 (Non-Insulin-Dependent) Diabetes Mellitus. [00:11] Type 1 Diabetes: Learn about the causes, symptoms (polyuria, polydipsia, polyphagia), and management of juvenile-onset diabetes. [00:52] Type 2 Diabetes: Understand the role of insulin resistance, genetics, and lifestyle factors in adult-onset diabetes. [01:35] Pathophysiology: A clear flowchart illustrating the progression of Type 2 Diabetes. [02:23] Long-Term Complications: Discover the systemic effects of diabetes on the brain, eyes, heart, kidneys, and more. [04:04] Diagnosis: A review of the diagnostic criteria, including blood glucose and HbA1c levels. [07:54] Management Strategies: An overview of glycemic control, lifestyle modifications (diet, exercise), and pharmacological treatments. [12:16] Diabetic Ketoacidosis (DKA): An in-depth look at this acute complication, including its causes, clinical features, and management. Part 2: Post-Transcriptional Modification [16:30] Introduction: An explanation of the processing of newly synthesized RNA in eukaryotic cells. [17:39] 5' Capping: Learn about the addition of a 7-methylguanosine cap and its role in mRNA stability. [18:50] 3' Poly-A Tailing: Understand the process and function of adding a poly-A tail to mRNA. [19:14] RNA Editing & Splicing: A discussion on the removal of introns and other modifications to the RNA sequence. [20:03] Clinical Significance: Discover how defects in these processes can lead to diseases like beta-thalassemia and cancer. SANTINIKETAN MEDICAL COLLEGE & HOSPITAL Real Classroom Demonstration/Lecture On: BIOCHEMISTRY by Prof.(Dr.) Tridibeswar Mandal (MBBS Batch: 2024-25) Conducted on: 16-07-25