Morning vs Evening BP Drugs: TIME & BedMed - Dr. Mackenzie, Dr. Hiremath, Dr. Garrison, Dr. Turgeon скачать в хорошем качестве

Morning vs Evening BP Drugs: TIME & BedMed - Dr. Mackenzie, Dr. Hiremath, Dr. Garrison, Dr. Turgeon

Dr. Ricky Turgeon (Vancouver, Canada), Dr. Scott Garrison (Edmonton, Canada), Dr. Swapnil Hiremath (Ottawa, Canada) and Dr. Isla Mackenzie (Dundee, UK) discuss the prognostic implications of morning vs evening intake of antihypertensive medication, based upon their TIME, BedMed and BedMed Frail studies and a subsequent metaanalysis, which were all presented as Late Breakers at the European Society of Cardiology annual meeting in 2022 (TIME) and 2024 (BedMed, BedMed Frail and the metaanalysis), subsequently. Dr. Ricky D Turgeon is a pharmacist and Assistant Professor at the University of British Columbia's Faculty of Pharmaceutical Sciences in Vancouver, Canada, and author of a metaanalysis on studies that compared morning vs evening medication intake in arterial hypertension. Dr. Scott Garrison is a family physician with a PhD in Experimental Medicine, Professor at the University of Alberta, Edmonton, Canada, founder of the Canadian Pragmatic Trials collaborative and PI of BedMed and BedMed Frail. Dr. Swapnil Hiremath is Nephrologist, Professor at the Faculty of Medicine, University of Ottawa, Canada, and Associate Scientist at Ottawa. Dr. Isla Mackenzie is Professor of Cardiovascular Medicine and Honorary Consultant Physician at the University of Dundee and Ninewells Hospital, Dundee, and first author of the TIME trial. The interview was recorded on November 5th, 2024. Moderators: Prof. Dr. Marlies Antlanger (Linz, Austria) and Gunnar Heine (Frankfurt, Germany). Articles discussed: Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial. Hermida RC, Crespo JJ, Domínguez-Sardiña M, Otero A, Moyá A, Ríos MT, Sineiro E, Castiñeira MC, Callejas PA, Pousa L, Salgado JL, Durán C, Sánchez JJ, Fernández JR, Mojón A, Ayala DE; Hygia Project Investigators. Eur Heart J 2020 doi: 10.1093/eurheartj/ehz754 Effect of timed dosing of usual antihypertensives according to patient chronotype on cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study. Pigazzani F, Dyar KA, Morant SV, Vetter C, Rogers A, Flynn RWV, Rorie DA, Mackenzie IS, Cappuccio FP, Manfredini R, MacDonald TM EClinicalMedicine 2024 doi: 10.1016/j.eclinm.2024.102633 The Hygia trial: Discussions about surprising results. Lüscher TF Eur Heart J 2020 doi: 10.1093/eurheartj/ehaa274 Lowering Nighttime Blood Pressure With Bedtime Dosing of Antihypertensive Medications: Controversies in Hypertension - Con Side of the Argument. Turgeon RD, Althouse AD, Cohen JB, Enache B, Hogenesch JB, Johansen ME, Mehta R, Meyerowitz-Katz G, Ziaeian B, Hiremath S Hypertension 2021 doi: 10.1161/HYPERTENSIONAHA.121.16501