Low Grade Fever - Causes and Diagnostic Approach скачать в хорошем качестве

Low Grade Fever - Causes and Diagnostic Approach

Low-grade fever (LGF) is defined as a body temperature between 37.5 degree Celsius or (99.5° Fahrenheit) and 38.3 degree Celsius or 100.3°F Fahrenheit (38.3°C). This temperature is below classical value reported for fever of unknow origin, but higher then normal temperature. If low grade fever has defined cause, then we treat underlying disease. If we can not define cause, then we act like in case of Fever of unknown origin. In case of Low grade fever, main focus is on Infectious diseases. Because in almost 60 % of cases it is caused by infections. Only 3 % of cases are neoplasm and malignancy. Around 6 % is non-infectious inflammatory disease. 18 % is miscellaneous causes. And 12 % is undiagnosed. Low grade fever also can be presented as atypical symptom of covid 19. Especially on recovery period which is called convalescence. At this cases low grade fever can lasts for several days during convalescence period. Low grade fever can have non specific signs and symptoms: signs and Symptoms of Low-Grade Fever Warm skin, A flushed face, Glassy eyes, Chills or Shivering, Sweating, Headache and Muscle Aches. Diagnosis of fever of unknown origin: First Step is Complete history and physical assessment. if we can define cause we can follow our findings. If We can not identify underlying cause, then do tests: Complete blood count, liver function, Blood Culture, Erythrocyte sedimentation rate, Urine analysis, Urine culture, Mantoux test for tuberculosis, and Chest Radiograph. If we still can not identified underlying cause then, CT scan of abdomen and pelvis, with contrast. Then Think accordingly. If malignancies is suspected then, biopsy, If autoimmune disease is suspected, define rheumatoid factor, ANA. PPD or Mantoux test should be done in all patients with fever of unknown origin. Its inexpensive and less invasive test. Which has high informative value. By Alexey Solodovnikov (Idea, Producer, CG, Editor), Valeria Arkhipova (Scientific Сonsultant) - Own work. Scientific consultants:Nikitin N.A., Doctor of Biological Sciences, Department of Virology, Faculty of Biology, Lomonosov Moscow State University.Borisevich S.S. Candidate of Chemical Sciences, Specialist in Molecular Modeling of Viral Surface Proteins, Senior Researcher, Laboratory of Chemical Physics, Ufa Institute of Chemistry RASArkhipova V.I., specialization in Fundamental and Applied chemistry, senior engineer, RNA Chemistry Laboratory, Institute of chemical biology and fundamental medicine SB RAS, CC BY-SA 4.0, https://commons.wikimedia.org/w/index...