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Here's a detailed write-up on Periosteum: Periosteum: A Protective Layer of Connective Tissue The periosteum is a thin layer of connective tissue that covers the outer surface of bones. It plays a vital role in bone growth, development, and repair. Structure The periosteum consists of two layers: 1. *Fibrous layer*: The outer layer, composed of dense fibrous connective tissue. 2. *Cambium layer*: The inner layer, composed of loose connective tissue with osteogenic cells. Functions The periosteum performs several important functions: 1. *Protection*: Shields the bone from injury and infection. 2. *Bone growth*: Provides a site for bone growth and development. 3. *Bone repair*: Aids in the repair of fractures by forming a callus. 4. *Nutrient supply*: Supplies nutrients and oxygen to the bone cells. 5. *Sensory function*: Contains nerve endings that detect pain, pressure, and vibration. Clinical significance Damage to the periosteum can lead to various conditions, including: 1. *Periostitis*: Inflammation of the periosteum. 2. *Periosteal reaction*: Abnormal bone growth or formation. 3. *Bone fractures*: Damage to the periosteum can impair bone healing. In conclusion, the periosteum is a vital layer of connective tissue that plays a crucial role in bone growth, development, and repair. Its functions are essential for maintaining healthy bones and overall skeletal health.