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Want to support the channel? Be a patron at: / lymed Welcome to LY Med, where I go over everything you need to know for the USMLE STEP 1, with new videos every day. Follow along with First Aid, or with my notes which can be found here: https://www.dropbox.com/sh/irs9b9ywx4... A big biochem video today. This vid will talk about DNA. This includes the structure of DNA, as well as how we can access it. Of course, no talk is complete without a discussion on DNA replication! We discuss the entire process, as well as the different components that play a role. Surprisingly, for something so complex, it rarely goes wrong. But when it does we call it mutations. These include: Silent mutations Missense mutations Nonsense mutations Frameshift mutations We close out by discussing how we fix and repair these mutations! We have a few different mechanisms and I will go over all of them here. These include mismatch repair and base excision repair.