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(23 Jun 2023) FOR CLEAN VERSION SEE STORY NUMBER: 4441189 ASSOCIATED PRESS Philadelphia – 24 May 2023 1. Tracking shot of Kensington Avenue HEADLINE: Animal sedative adds new pain to opioid crisis 2. Tracking shot of tents on street 3. A man on street ANNOTATION: A powerful animal sedative in the illicit drug supply is complicating the U.S. response to the opioid crisis. 4. Pedestrians on Kensington ANNOTATION: Xylazine, called "tranq," is often mixed with fentanyl. It can cause gruesome severe skin wounds. 5. A man receiving a wound care at Savage Sisters’ storefront 6. A nurse cleaning a wound 7. Cut away of bandages being cut 8. A woman receiving wound care 9. A nurse placing bandage over a wound on hand ++SOUNDBITE COVERED++ 10. SOUNDBITE (English) Sarah Laurel, founder of Savage Sisters: “So, xylazine is an animal grade tranquilizer that is commonly used to adulterate the heroin and fentanyl supply. So, unfortunately, we are seeing the long-term use of xylazine is causing large open ulcers on our friends, and that's leading to the wound becoming necrotic, which means dead tissue and eventually amputation. And it was originally put in there to give the suply legs, to make that euphoric feeling last longer. It causes high sedation.” 11. Mid of Laurel 12. Wide of Sarah Laurel, founder of Savage Sisters, at the group’s storefront in Kensington ANNOTATION: Savage Sisters provides outreach and care to people with addiction. The group says xylazine is making the drug crisis worse. 13. SOUNDBITE (English) Sarah Laurel, founder of Savage Sisters: “So, nobody asked for xylazine in the drug supply and before anybody knew it, everyone, like the community is now chemically dependent on it. So, yes, people do seek it out because they are dependent on it. And it has become the main supply.” ASSOCIATED PRESS Philadelphia – 23 May 2023 14. Ellwood Warren walking into a wound care van ANNOTATION: Local health workers drive around in vans to treat skin wounds caused by tranq. 15. Warren showing his wounds to the nurse ANNOTATION: The wounds make it hard to get people into rehabilitation programs, which aren't equipped to treat lesions. 16. Warren’s arm 17. SOUNDBITE (English), Kathy Lalli, nurse , Kensington Hosptial: “All these are wounds from tranq, O.K? So you know what is the tranq, right? (Ellwood said, “xylazine?”) Even though you inject there, it comes wherever it wants to come out.” 18. SOUNDBITE (English) Ellwood Warren, patient: “I can see what it’s doing to me. I mean, it's deteriorated my health and my body tremendously almost overnight, you know.” ASSOCIATED PRESS New York – 30 May 2023 19. Dr. Jennifer Love, Emergency Medicine Physician at The Mount Sinai Hospital 20. Cut away of hospital equipment ANNOTATION: It's not yet clear if xylazine is leading to more deaths. Some research suggests it may inadvertently be diluting the effects of fentanyl. 21. SOUNDBITE (English) Dr. Jennifer Love, Mount Sinai Hospital: “Xylazine exposure in an overdose might not be as dangerous as we expect, we still have to understand the short and long-term effects of Xylazine on our patients. There may be long-term health effects that we don’t yet know about that could be very severe and very harmful for patients. And once we understand them better, we will be able to better care for our patients when we see them.” ASSOCIATED PRESS Philadelphia – 24 May 2023 22. Wide of Savage Sisters’ storefront in Kensington 23. Mid of Laurel 24. Silhouette of people inside Savage Sisters drop-in house with a man on wheelchair outside 25. Mid of a man’s leg Find out more about AP Archive: http://www.aparchive.com/HowWeWork Twitter: / ap_archive Facebook: / aparchives Instagram: / apnews You can license this story through AP Archive: http://www.aparchive.com/metadata/you...