Effect of Neonatal Sepsis On Neurodevelopment of Infants in Uganda ENON Neuroimaging Findings скачать в хорошем качестве

Effect of Neonatal Sepsis On Neurodevelopment of Infants in Uganda ENON Neuroimaging Findings

Research Talk - November 30, 2023 Speaker: Dr David Mukunya, Senior Lecturer, Department of Community and Public Health, Busitema University (Uganda) Over 250 million children in low- and middle-income countries (LMICs) do not fulfill their neurodevelopmental potential. This can result in poor school performance and a cycle of intergenerational poverty. Interventions delivered to children under 5-years can improve neurodevelopmental outcomes. It is therefore vital to identify factors that increase the risk of long term difficulties. There is a paucity of data on the effects of early infections as a risk for neurodevelopmental delay, thus limiting the development of timely and targeted interventions to improve outcomes. In the last decade (2009-2018), the incidence of neonatal sepsis in LMICs was 4000 cases per 100,000 live births. This number may increase with more babies being born early and infections becoming resistant to antibiotics. In addition to the high case fatality associated with neonatal sepsis, survivors may suffer from long-term neurodevelopmental delays and medical conditions, includingpost-infectious hydrocephalus and cerebral palsy, although these neurodevelopment effects are not well documented,especially in sub-Saharan Africa. This talk will present preliminary results, which compare neurodevelopment and neuroimaging findings from 3-6 months, between infants who were hospitalized for neonatal sepsis and infants who did not suffer from it.