How Does Taste Work? - Taste Receptors - Salt, Sweet, Bitter, Sour, Umami скачать в хорошем качестве

How Does Taste Work? - Taste Receptors - Salt, Sweet, Bitter, Sour, Umami

Taste, or gustation, is the sense that receives information from molecules and ions in our food. The five main types of taste are sweet, umami, bitter, sour, and salty. The first three are all detected through G-protein coupled receptors (GPCR) while sour and salty are sensed through ion channels - sour via hydrogen ion channels and salt via sodium ion channels. In this video I go into detail about how taste is sensed while giving brief overviews of general biochemical processes of ion channels, action potentials, and G-protein coupled receptors. Other places you can find content from me: Patreon - authortomharper   / authortomharper   Blog - The Cynical Philosopher https://authortomharper.com/ Twitter - @AuthorTomHarper   / authortomharper   Amazon - Author Profile https://www.amazon.com/Thomas-Harper/... My science fiction series available on Amazon Incarnate: Existence Incarnate: Essence Incarnate: Schism References Human Biology of Taste https://www.researchgate.net/publicat... Taste buds: cells, signals and synapses https://www.ncbi.nlm.nih.gov/pmc/arti... Salty Taste: From Transduction to Transmitter Release, Hold the Calcium https://www.cell.com/action/showPdf?p... The taste of table salt https://www.ncbi.nlm.nih.gov/pmc/arti... Cellular and Neural Responses to Sour Stimuli Require the Proton Channel OTOP1 https://www.cell.com/current-biology/... Otopetrin-1: A sour-tasting proton channel https://www.ncbi.nlm.nih.gov/pmc/arti... pHirst sour channels pHound? https://www.ncbi.nlm.nih.gov/pmc/arti... Sour taste finds closure in a potassium channel https://www.pnas.org/content/113/2/246 The candidate sour taste receptor, PKD2L1, is expressed by type III taste cells in the mouse https://www.ncbi.nlm.nih.gov/pmc/arti... Common Sense about Taste: From Mammals to Insects https://www.cell.com/fulltext/S0092-8... Taste Receptors and the Transduction of Taste Signals https://www.ncbi.nlm.nih.gov/books/NB... Molecular principles of assembly, activation, and inhibition in epithelial sodium channel https://elifesciences.org/articles/59038 Structural basis for perception of diverse chemical substances by T1r taste receptors https://www.nature.com/articles/ncomm... Multimodal Ligand Binding Studies of Human and Mouse G-Coupled Taste Receptors to Correlate Their Species-Specific Sweetness Tasting Properties https://www.mdpi.com/1420-3049/23/10/... Functional roles of the sweet taste receptor in oral and extraoral tissues https://www.researchgate.net/publicat... The neuroscience of sugars in taste, gut-reward, feeding circuits, and obesity https://www.researchgate.net/publicat... An Evolutionarily Conserved Gene Family Encodes Proton-Selective Ion Channels https://www.ncbi.nlm.nih.gov/pmc/arti... Structures of the Otopetrin Proton Channels Otop1 and Otop3 https://www.ncbi.nlm.nih.gov/pmc/arti... A taste for ATP: neurotransmission in taste buds https://www.frontiersin.org/articles/... X-ray structures define human P2X3 receptor gating cycle and antagonist action https://www.ncbi.nlm.nih.gov/pmc/arti... Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction https://www.mdpi.com/2072-6643/8/5/17... Nernst Equilibrium Potential https://www.physiologyweb.com/lecture... Resting Membrane Potential https://courses.lumenlearning.com/wm-... What is an Action Potential? https://www.moleculardevices.com/appl... Crystal structure of the β2 adrenergic receptor–Gs protein complex https://www.ncbi.nlm.nih.gov/pmc/arti... PDB Codes 6BQN – Epithelial Sodium Channel (ENaC) 6WTH – Epithelial Sodium Channel (ENaC) 6NF4 – Otop1 5X2O – T1R2a/T1R3 5SVK – P2X3 ATP Receptor 5SVL – P2X3 ATP Receptor