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Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this endocrine physiology lecture, Professor Zach Murphy delivers a complete overview of the adrenal gland, integrating its anatomy, hormone production, and regulatory pathways. This lecture ties together the distinct roles of the adrenal cortex and adrenal medulla, highlighting how this small organ orchestrates major homeostatic functions across the body. We begin with a breakdown of the three zones of the adrenal cortex—zona glomerulosa, zona fasciculata, and zona reticularis—each responsible for producing a specific class of hormones: aldosterone (mineralocorticoid), cortisol (glucocorticoid), and androgens (gonadocorticoids), respectively. You’ll learn how these hormones regulate fluid balance, metabolism, immune response, and secondary sex characteristics, along with the feedback loops that control their secretion. The lecture then transitions to the adrenal medulla, where chromaffin cells secrete epinephrine and norepinephrine under sympathetic stimulation, driving the body’s acute fight-or-flight response. We tie in the synthesis, action, and receptor signaling of catecholamines and their interaction with cortical hormones for integrated stress adaptation. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #AdrenalGland #AdrenalGlandOverview