Dr. Gilbert Hosts: Pre-motor Parkinson’s Disease скачать в хорошем качестве

Dr. Gilbert Hosts: Pre-motor Parkinson’s Disease

In this session of Dr. Gilbert Hosts, Dr. Gilbert had an eye-opening conversation with special guests Dr. Michael Schwarzschild, along with Stacey Mihaly and Charles Walker, two people living with Parkinson’s disease. They discussed how Parkinson’s may begin long before the first tremor appears, and answered audience questions live. 3:36 Dr. Schwarzchild’s presentation 19:13 Stacey Mihaly’s presentation 25:43 Chuck Walker’s story 29:07 Is it common to have phantom smells as part of pre-motor Parkinson’s disease? 31:04 What if someone occasionally yells in their sleep but does not act out their dreams – is that considered REM behavior sleep disorder? 32:42 How many people in the prodromal stage of PD will have a positive result on the alpha-synuclein seed amplification assay or the alpha-synuclein skin biopsy? 36:16 Are changes in speech considered a prodromal or premotor symptom of PD? 40:14 Are there any interventions/therapies available to slow progression that are available to people with prodromal PD? 43:12 Sometimes, subtle undiagnosed symptoms declare themselves as PD in the setting of another medical problem. Can you explain how this happens? 47:27 Can apathy be a premotor symptom of PD? When does Parkinson’s disease really begin? For years, a Parkinson’s disease (PD) diagnosis has focused on visible symptoms like tremor, slowness, stiffness, and walking challenges. But we also know that the pathological changes that accompany PD start decades earlier. These changes can result in more hidden signs, like smell loss, constipation, and certain sleep disorders (known collectively as pre-motor or non-motor symptoms). These early clues, combined with exciting breakthroughs in biomarkers and genetics, are transforming our understanding of Parkinson’s and opening new doors for earlier detection and intervention. Watch and you'll learn: What are the pre-motor symptoms of PD, and why do they matter? What steps can you take if you or a loved one is experiencing early, non-- motor symptoms? Should PD be diagnosed based on biomarkers and not based on clinical exam? Can a clinical trial aim to prevent PD in someone who is at high risk of developing PD? And much more! Let's Stay Connected 1) SUBSCRIBE to our YouTube Channel to stay informed about other APDA videos. 2) Turn ON YouTube Notifications to get alerts whenever we go live or upload new content. 3) Connect with APDA on Facebook, Instagram, Twitter, or LinkedIn at @APDAparkinsons.